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Why does pregnancy not occur even after transferring a grade A embryo?

Why does pregnancy not occur even after transferring a grade A embryo?

The issues preventing embryo implantation should be addressed by seeking appropriate treatment as follows;

 

• An embryo that appears to be growing well, or grade A embryo, may have abnormal chromosomes. It is recommended to transfer an embryo that has been tested for chromosome abnormality to increase the success rate of pregnancy.

 

• It could be caused by abnormalities in the uterus or fallopian tubes, including abnormal uterine shape, intrauterine adhesions, polyps, uterine fibroids. chronic endometritis, and edema of the fallopian tubes causing them to be filled with fluid, preventing the embryo from implanting. These issues should be solved via treatment or surgery before an embryo

 

• Intake duration and the level of progesterone must be evaluated to determine the “window of implantation”, ensuring that the endometrial lining is ready for embryo implantation to increase the chance of pregnancy.

 

• It is recommended to have examinations for immune conditions that may affect embryo implantation and tests for the levels of thyroid hormones and vitamin D. This is to ensure that the body is in an optimum condition conducive to embryo implant There should also be lifestyle modifications for better physical health and maintainance of an appropriate body weight.

 

• Consider using “Embryo Glue”, an embryo transfer medium containing hyaluronic acid which has implantation promoting properties. Granulocyte–colony stimulation factor (G-CSF) injections may help to promote endometrium development to be optimal for embryo
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